YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

ENTREZID: 7534 | Type: NA | Map: 8q22.3

Summary Entrez
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5’ UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]