PTBP1


polypyrimidine tract binding protein 1


Gene Context Sentence


Table 2. Analysis of context sentence of PTBP1 gene in 1 abstracts.

PMID Gene Context Sentence
33254518 The purpose of this report is to explore the limited yet salient current evidence that SARS-CoV-2’s host genomic targets PTBP1 and the 14-3-3 protein isoform encoding genes YWHAE and YWHAZ may be hold the key to understanding how neurotropism triggers neurodegeneration and how it may contribute to the onset of neurodegenerative disease. […] Considering that PTBP1 silencing in particular has recently been shown to reverse clinical parkinsonism and induce neurogenesis, as well as the known interactions of PTBP1 and YWHAE/Z with coronaviruses - most notably 14-3-3 and SARS-CoV, recent studies reinvigorate the infectious etiology hypotheses on major neurodegenerative disease such as AD and iPD.