alanyl aminopeptidase, membrane

Gene Context Sentence

Table 2. Analysis of context sentence of ANPEP gene in 9 abstracts.

PMID Gene Context Sentence
32199615 Intriguingly, we found that the candidate co-receptors, manifesting the most similar expression patterns with ACE2 across 13 human tissues, are all peptidases, including ANPEP, DPP4 and ENPEP. […] Among them, ANPEP and DPP4 are the known receptors for human CoVs, suggesting ENPEP as another potential receptor for human CoVs.
32374427 In this study, a total of 38 conjunctival samples from 38 patients, including 12 healthy conjunctiva, 12 melanoma, 7 squamous cell carcinoma and 7 papilloma samples, were analyzed using high-throughput RNA sequencing to assess mRNA expression of the SARS-CoV-2 receptor ACE2 and its cofactors including TMPRSS2, ANPEP, DPP4, and ENPEP.
32463365 We find the gut as the putative hotspot of COVID-19, where a maturation correlated transcriptional signature is shared in small intestine enterocytes among coronavirus receptors(ACE2, DPP4, ANPEP).
32581077 Different inflammatory genes mined here, including TNFR, IL-8, CXCR1, CXCR2, ADAM10, GPR84, MME, ANPEP, and LAP3, might be druggable targets in efforts to limit SARS-CoV-2 inflammation in severe clinical cases.
32589459 Other receptors such as ANPEP, AGTR2 are expressed at low level in the conjunctiva.
32894568 The corresponding three genomic phases include the “ACE2, ANPEP transcripts in the initial phase”, “EGFR and IGF2R transcripts in the propagating phase” and the “immune system related critical gene involvements of the complicating phase”. […] ANPEP gene pathway may have a potential for the vaccine development.
32974340 Other coronavirus family receptors (ANPEP and DPP4) were also expressed in the first and second trimester placental cells. […] Additionally, the term placenta of multiple species including humans expressed ACE2, DPP4, and ANPEP along with the viral S protein proteases.
33313148 Compared with the other coronavirus receptors, such as aminopeptidase N (ANPEP) or dipeptidyl peptidase 4 (DPP4), the mRNA and protein expression of ACE2 was increased in the heart.
33564056 In this study, we investigated the variability of four genes (ACE2, ANPEP and DPP4 encoding for host receptors of the viral spike proteins and TMPRSS2 encoding for a host proteinase) in 23 European (19 autochthonous and three commercial breeds and one wild boar population) and two Asian Sus scrofa populations.