SCAP


SREBF chaperone


Gene Context Sentence


Table 2. Analysis of context sentence of SCAP gene in 3 abstracts.

PMID Gene Context Sentence
32805298 While the world is grappling with the consequences of a global pandemic related to SARS-CoV-2 causing severe pneumonia, available evidence points to bacterial infection with Streptococcus pneumoniae as the most common cause of severe community acquired pneumonia (SCAP). […] In this review, we focus on the risk factors, microbiology, site of care decisions and treatment of patients with SCAP.
33170499 Metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) has the potential to improve the pathogen identification in severe community-acquired pneumonia (SCAP). […] In this 1.5-year, multicenter, prospective study, we investigated the usefulness of mNGS of BALF for identifying pathogens of SCAP in hospitalized adults, comparing it with other laboratory methods. […] Of 329 SCAP adults, a microbial etiology was established in 304 cases (92.4%). […] A high microbial detection rate was achieved in SCAP adults using mNGS testing of BALF. […] The most frequently detected pathogens of SCAP differed between immunocompetent and immunocompromised patients. mNGS testing may be an powerful tool for early identification of potential pathogens for SCAP to initiate a precise antimicrobial therapy.
33417280 The severity of the disease according to ICMR protocol for COVID-19, the PSI/PORT score, the CURB-65 score and the SCAP score were calculated in all the patients and analysed with the disease outcome, that is, 14-day mortality. […] SCAP score, PSI/PORT score and CURB-65 criteria, all were good indicators of disease severity and 14-day mortality. […] However, when compared to other scoring systems, SCAP score was a more accurate marker of disease severity and 14-day mortality. […] The PSI/PORT scoring system, the CURB-65 criteria and the SCAP scoring system can be used to assess the COVID-19 severity and predict the 14-day mortality risk in cases of COVID-19 pneumonia.