DrugBank ID: db02134
DrugCentral: xanthine
Synonymous : None

Drug Sentece Context

Table 1. Analysis of context sentence of xanthine gene in 7 abstracts.

pmid sentence
32473070 Pentoxifylline is a methyl-xanthine and it inhibits phosphodiesterase IV (PDE IV).
32536670 Favipiravir is metabolized to an inactive metabolite M1 by aldehyde oxidase and xanthine oxidase, and excreted into urine.
32787748 Pentoxifylline is an inhibitor of TNF-α production and oxypurinol inhibits xanthine oxidase.
32840387 In MA-induced OA rat, the tumor necrosis factor alpha, interleukin 6, C-reactive protein, rheumatoid factors, reactive oxygen species, as well as all the mitochondrial markers such as mitochondria membrane potential, swelling mitochondria, cytochrome c oxidase (complex IV), and serum oxidative/antioxidant status (malondialdehyde level and activities of myeloperoxidase and xanthine oxidase) are elevated.
33129363 • Clinical prognostic non-survival, palliative care, or in deep coma and no have response to supportive treatment within three hours of admission • Patient with irregular rhythm • Patient with a history of heart attack (myocardial infarction) • Patient with a family history of sudden death from heart attack before the age of 50 • Take other drugs that can cause prolonged QT interval • Patient who is receiving immunosuppressive therapy (cyclosporin) which cannot be switched to another agent or adjusted while using the investigational drug • Gout/history of Gout or hyperuricemia (above the ULN), hereditary xanthinuria or xanthine calculi of the urinary tract.