VIOMYCIN
DrugBank ID: db06827
DrugCentral: viomycin
Synonymous :vinacetin a | viomicina | viomycin | viomycine | viomycinum
Drug Sentece Context
Table 1. Analysis of context sentence of viomycin gene in 2 abstracts.
| pmid | sentence |
|---|---|
| 32406317 | The study revealed that Viomycin showed the highest -CDocker energy after docking at the active site of SARS-CoV-2 Main Protease. […] It is noteworthy that Viomycin showed higher -CDocker energy as compared to the drugs currently under clinical trial for SARS-CoV-2 treatment viz. Ritonavir and Lopinavir. […] Additionally, Viomycin formed higher number of H-bonds with SARS-CoV-2 Main Protease than its co-crystallised inhibitor compound N3. […] Molecular dynamics simulation further showed that Viomycin embedded deeply inside the binding pocket and formed robust binding with SARS-CoV-2 Main Protease. […] Therefore, we propose that Viomycin may act as a potential inhibitor of the Main Protease of SARS-CoV-2. |
| 32909528 | Based on virtual screening technology and molecular dynamics simulation, we found 23 approved clinical drugs such as Viomycin, Capastat, Carfilzomib and Saquinavir, which showed high affinity with the 3CLpro active sites. |