DrugBank ID: db00679
DrugCentral: thioridazine
Synonymous :10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine | 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazine | 3-methylmercapto-n-(2’-(n-methyl-2-piperidyl)ethyl)phenothiazine | thioridazin | thioridazine | thioridazinum | tioridazina

Drug Sentece Context

Table 1. Analysis of context sentence of thioridazine gene in 4 abstracts.

pmid sentence
32493475 Weight less than 40 Kg.Participant with any immunosuppressive condition or hematological disease.Treatment with drugs that may prolong QT in the last month before randomization for more than 7 days including: azithromycin, chlorpromazine, cisapride, clarithromycin, domperidone, droperidol, erythromycin, halofantrine, haloperidol, lumefantrine, mefloquine, methadone, pentamidine, procainamide, quinidine, quinine, sotalol, sparfloxacin, thioridazine, amiodarone.Hereditary intolerance to galactose, Lapp lactase deficiency or glucose or galactose malabsorption.Treatment with fluvoxamine.Treatment with benzodiazepines or benzodiazepine analogues such as zolpidem, zopiclone or zaleplon.Pregnancy.Breastfeeding.History of potentially immune derived diseases such as: lupus, Crohn’s disease, ulcerative colitis, vasculitis or rheumatoid arthritis.Insulin-dependent diabetes mellitus.Known history of hypersensitivity to the study drug or any of its components.Patients that should not be included in the study at the judgment of the research team.
32829256 Our results reveal that thioridazine and its identified photoproducts (mesoridazine and sulforidazine) have high biological activity on the virus Mpro. […] This shows that thioridazine and its two photoproducts might represent new potent medicines to be used for treatment in this outbreak.
32949606 The goal of this paper was to summarize the current literature on activity toward RNA-viruses of such drugs like chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine. […] Chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine possess anti-viral activity towards different types of viruses.
33324406 These screens have identified 20 anti-SARS-CoV-2 drugs including previously reported compounds such as hydroxychloroquine, amlodipine besylate, arbidol hydrochloride, tilorone 2HCl, dronedarone hydrochloride, mefloquine, and thioridazine hydrochloride.