PYRIDOSTIGMINE


DrugBank ID: db00545
DrugCentral: pyridostigmine
Synonymous :piridostigmina | pyridostigmine cation



Drug Sentece Context


Table 1. Analysis of context sentence of pyridostigmine gene in 4 abstracts.

pmid sentence
33066761 Pyridostigmine (PDG), an ACh-esterase inhibitor (i-ACh-e), increases the half-life of endogenous ACh, therefore mimicking the inflammatory reflex. […] A parallel-group, multicenter, randomized, double-blinded, placebo-controlled, phase 2/3 clinical trial to test the efficacy of pyridostigmine bromide 60 mg/day P.O. to reduce the need for invasive mechanical ventilation and mortality in hospitalized patients with severe COVID-19.
33421278 The patient was treated with pyridostigmine (60 mg four times a day) with unsatisfactory clinical response, followed by immunosuppressive therapy (azathioprine 1.5 mg/kg/day) with improvement of MG symptoms after two months of treatment.