DrugBank ID: db00339
DrugCentral: pyrazinamide
Synonymous :2-carbamylpyrazine | 2-pyrazinecarboxamide | aldinamide | pirazinamida | pirazinamide | pyrazinamid | pyrazinamida | pyrazinamide | pyrazinamidum | pyrazine carboxamide | pyrazine-2-carboxamide | pyrazineamide | pyrazinecarboxamide | pyrazinoic acid amide | pyrizinamide

Drug Sentece Context

Table 1. Analysis of context sentence of pyrazinamide gene in 1 abstracts.

pmid sentence
33050924 Exclusion criteria are: Inability to make an informed decision to participate (e.g.: dementia, guardianship); Rockwood Clinical Frailty Scale ≥7; Long QT syndrome; QTc interval > 500 ms; Heart rate <50/min; Kalaemia >5.5 mmol/L or <3.5 mmol/L; Ongoing treatment with piperaquine, halofantrine, dasatinib, nilotinib, hydroxyzine, domperidone, citalopram, escitalopram, potent inhibitors or inducers of cytochrome P450 CYP3A4 isoenzyme, repaglinide, azathioprine, 6-mercaptopurine, theophylline, pyrazinamide, warfarin; Known hypersensitivity to any of the trial drugs or to chloroquine and other 4-aminoquinolines, amodiaquine, mefloquine, glafenine, floctafenine, antrafenine, ARB; Hepatic porphyria; Liver failure (Child-Pugh stage ≥B); Stage 4 or 5 chronic kidney disease (GFR <30 mL/min/1.73 m²); Dialysis; Hypersentivity to lactose; Lactase deficiency; Abnormalities in galactose metabolism; Malabsorption syndrome; Glucose-6-phosphate dehydrogenase deficiency; Symptomatic hyperuricemia; Ileus; Colitis; Enterocolitis; Chronic hepatitis B virus disease.