DrugBank ID: db00120
DrugCentral: phenylalanine
Synonymous :(s)-2-amino-3-phenylpropionic acid | (s)-alpha-amino-beta-phenylpropionic acid | 3-phenyl-l-alanine | beta-phenyl-l-alanine | f | fenilalanina | l-phenylalanine | phe | phenylalanine | phenylalaninum | β-phenyl-l-alanine

Drug Sentece Context

Table 1. Analysis of context sentence of phenylalanine gene in 5 abstracts.

pmid sentence
32081428 A unique phenylalanine F486 in the flexible loop likely plays a major role because its penetration into a deep hydrophobic pocket in ACE2.
32493627 The presence of glutamine, asparagine, leucine, phenylalanine and serine amino acids in SARS-CoV-2 enhances ACE2 binding.
32723797 Through comparative structural analysis of the wild-type and mutant proteins, we showed that this addition of a phenylalanine residue renders the protein in the mutant less stable, which might affect mRNA cap-1 methyltransferase function.
32955901 Phenylalanine, tyrosine, glycine, lysine, and aspartic acid were found to be the headliner amino acids in the interactions between Arbidol and binding domains of spike glycoproteins in the SARS-CoV2 (Tab.
33177698 The protein deviates from the ideal α-helical geometry due to three phenylalanine residues, which stack within each helix and between helices.
33207699 An untargeted analysis of non-critical COVID-19 patients identified a strong alteration of lipids and a perturbation of phenylalanine, tyrosine and tryptophan biosynthesis, phenylalanine metabolism, aminoacyl-tRNA degradation, arachidonic acid metabolism, and the tricarboxylic acid (TCA) cycle.