LAMIVUDINE


DrugBank ID: db00709
DrugCentral: lamivudine
Synonymous :(-)-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine | (-)-2’-deoxy-3’-thiacytidine | 2’,3’-dideoxy-3’-thiacytidine | 3’-thia-2’,3’-dideoxycytidine | 3tc | beta-l-2’,3’-dideoxy-3’-thiacytidine | beta-l-3’-thia-2’,3’-dideoxycytidine | lamivudin | lamivudina | lamivudine | lamivudinum



Drug Sentece Context


Table 1. Analysis of context sentence of lamivudine gene in 5 abstracts.

pmid sentence
32429580 These agents included tenofovir (TFV), 4’-ethynyl-2-fluoro-2’-deoxyadenosine (EFdA), alovudine (FLT), lamivudine (3TC), and emtricitabine (FTC), known as nucleoside reverse-transcriptase inhibitors (NRTIs), and a number of 5’-O-fatty acylated anti-HIV nucleoside conjugates.
32437000 A 34 year old HIV-positive female on antiretroviral therapy (tenofovir disoproxil fumarate, lamivudine and efavirenz) for 5 years, tested positive for SARS-CoV-2, the causative agent for coronavirus disease 19 (COVID-19).
32589451 Risk and 95% CIs for COVID-19 diagnosis and hospital admission by use of the NRTIs tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC), tenofovir alafenamide (TAF)/FTC, abacavir (ABC)/lamivudine (3TC), and others were estimated through Poisson regression models.
32692185 Using the molecular insight gained from the previous studies, we selected the active triphosphate forms of six other antiviral agents, Alovudine, Tenofovir alafenamide, AZT, Abacavir, Lamivudine, and Emtricitabine, for evaluation as inhibitors of the SARS-CoV-2 RdRp and demonstrated the ability of these viral polymerase inhibitors to be incorporated by SARS-CoV-2 RdRp, where they terminate further polymerase extension with varying efficiency.
32866436 Herein we present the case of a 63-year-old HIV-infected woman with undetectable viral load, on dolutegravir, tenofovir and lamivudine, who was hospitalized due to COVID-19 pneumonia.
32866780 These are antidiabetic (acarbose), vitamins (riboflavin and levomefolic acid), anti-platelet agents (cangrelor), aminoglycoside antibiotics (Kanamycin, amikacin) bronchodilator (fenoterol), immunomodulator (lamivudine), and anti-neoplastic agents (mitoxantrone and vidarabine).
33080984 We also found that combinations of sofosbuvir with brequinar or niclosamide are synergistic against HCV infection in hepatocyte-derived Huh-7.5 cells, and that combinations of monensin with lamivudine or tenofovir are synergistic against HIV-1 infection in human cervical TZM-bl cells.