CANNABIDIOL


DrugBank ID: db09061
DrugCentral: cannabidiol
Synonymous :(−)-trans-2-p-mentha-1,8-dien-3-yl-5-pentylresorcinol | (−)-trans-cannabidiol | (1’r,2’r)-5’-methyl-4-pentyl-2’-(prop-1-en-2-yl)-1’,2’,3’,4’-tetrahydrobiphenyl-2,6-diol | cannabidiol | cbd | δ1(2)-trans-cannabidiol



Drug Sentece Context


Table 1. Analysis of context sentence of cannabidiol gene in 6 abstracts.

pmid sentence
32519753 We suggest the hypothesis that Cannabidiol (CBD), a non-psychotropic phytocannabinoid, has the potential to limit the severity and progression of the disease for several reasons: 1) High-CBD Cannabis Sativa extracts are able to downregulate the expression of the two key receptors for SARS-CoV2 in several models of human epithelia 2) CBD exerts a wide range of immunomodulatory and anti-inflammatory effects and it can mitigate the uncontrolled cytokine production featuring Acute Lung Injury 3) Being a PPARγ agonist, it can display a direct antiviral activity 4) PPARγ agonists are regulators of fibroblast/myofibroblast activation and can inhibit the development of pulmonary fibrosis, thus ameliorating lung function in recovered patients.
32699671 Many cannabidiol (CBD) retailers make unsupported medical claims about their product.
32804502 This Perspective of the published essential medicinal chemistry of cannabidiol (CBD) provides evidence that the popularization of CBD-fortified or CBD-labeled health products and CBD-associated health claims lacks a rigorous scientific foundation.
32923657 Among all cannabinoids, cannabidiol (CBD) has demonstrated potent anti-inflammatory effects in a variety of pathological conditions.
33001829 There is some scientific evidence that vaping, cannabidiol (CBD - an active ingredient in cannabis from the hemp plant) or other substances, may be associated with more severe manifestations of COVID-19.
33058425 In a follow-up study to our recent findings indicating the potential of Cannabidiol (CBD) in the treatment of acute respiratory distress syndrome (ARDS), here we show for the first time that CBD may ameliorate the symptoms of ARDS through up-regulation of apelin, a peptide with significant role in the central and peripheral regulation of immunity, CNS, metabolic and cardiovascular system.
33245701 Cannabidiol can both directly and indirectly improve immunity by enhancing natural killer cell activity, reducing inflammation, and relieving stress.
33267756 However, the approval of some cannabinoids by the FDA (along with other recognized national medical health systems) has opened the horizons for the explicit use of these natural drugs in medicines such as Epidiolex® (cannabidiol used for the treatment of severe forms of epilepsy) and Sativex®(‘Δ9 -tetrahydrocannabinol and cannabidiol’ used for the treatment of spasticity caused by multiple sclerosis, aka: MS.) […] Many pharmacological properties of C. sativa are attributed to cannabidiol (CBD), a non-psychoactive component, along with Δ9 -tetrahydrocannabinol (Δ9 -THC), a psychoactive component.
33323690 Cannabis products such as cannabidiol (CBD) are being advertised for the treatment of COVID-19 associated mental health problems and substance use disorders.
33363552 Specifically, hemp contains terpenophenolic compounds such as cannabidiol (CBD) and cannabigerol (CBG), which act on cannabinoid receptors and positively regulate various human metabolic, immunological, and physiological functions.
33584697 -THC), cannabidiol (CBD), and synthetic cannabinoids; however, the mechanisms remain unclear.