BRILACIDIN
DrugBank ID: db12997
DrugCentral: brilacidin
Synonymous :brilacidin | brilacidina | brilacidine | brilacidinum
Drug Sentece Context
Table 1. Analysis of context sentence of brilacidin gene in 4 abstracts.
| pmid | sentence |
|---|---|
| 33572467 | In this manuscript, we describe the potent antiviral activity exerted by brilacidin-a de novo designed synthetic small molecule that captures the biological properties of HDPs-on SARS-CoV-2 in a human lung cell line (Calu-3) and a monkey cell line (Vero). […] These data suggest that SARS-CoV-2 inhibition in these cell culture models is likely to be a result of the impact of brilacidin on viral entry and its disruption of viral integrity. […] Brilacidin demonstrated synergistic antiviral activity when combined with remdesivir. […] Collectively, our data demonstrate that brilacidin exerts potent inhibition of SARS-CoV-2 against different strains of the virus in cell culture. |