DrugBank ID: db00174
DrugCentral: asparagine
Synonymous :(2s)-2-amino-3-carbamoylpropanoic acid | (2s)-2,4-diamino-4-oxobutanoic acid | (s)-2-amino-3-carbamoylpropanoic acid | (s)-asparagine | 2-aminosuccinamic acid | alpha-aminosuccinamic acid | asn | asparagine | aspartamic acid | l-2-aminosuccinamic acid | l-asparagine | l-aspartic acid beta-amide | l-aspartic acid β-amide | α-aminosuccinamic acid

Drug Sentece Context

Table 1. Analysis of context sentence of asparagine gene in 7 abstracts.

pmid sentence
32493627 The presence of glutamine, asparagine, leucine, phenylalanine and serine amino acids in SARS-CoV-2 enhances ACE2 binding.
32679775 The spontaneous conversion of asparagine (Asn) residues to aspartic acid or isoaspartic acid is a frequent modification in proteins as part of the process called deamidation.
32753553 By using deep mutagenesis, mutations in ACE2 that increase S binding are found across the interaction surface, in the asparagine 90-glycosylation motif and at buried sites.
32979815 The relative binding poses of Z93 fitted well in the binding site of both proteases and showed consensus π-π stacking and H-bond interactions with histidine and aspartate/asparagine residues of the catalytic triad.
33578036 Using this bioreporter, we uncovered critical host and viral determinants of the interaction, including a role for glycosylation of asparagine residues within the RBD in mediating successful viral entry.
33587268 One prominent adaptive mutation is the asparagine-to-glycine substitution at amino acid position 614 in the viral spike protein (D614G), which has become dominant in the currently circulating virus strains.